Tuberculosis-Diabetes co-morbidity

Tuberculosis (TB) remains a major cause of morbidity and mortality in low- and middle-income countries

  • In 2014, 9.6 million estimated TB cases and 1.5 million deaths
  • South Africa is the 3rd highest TB incidence in the world with 834 per 100 000 (WHO, 2015)
  • 318 000 cases notified in 2014 (WHO, 2015).

TB is fueled by different medical, social, and economic factors

  • HIV
  • Poverty
  • Malnutrition
  • Overcrowding and many others

Diabetes Mellitus is a major public health problem.

  • Type 2 diabetes accounting >90% of DM cases.
  • The insidious and initially asymptomatic nature of the disease results in persons not seeking early medical attention (30-85% of cases of type 2 diabetes are undiagnosed).
  • At diagnosis, approximately 20% of patients will have complications of the disease.
  • Effects of urbanization and an unhealthy lifestyle are important contributors to the rising prevalence of obesity and diabetes
  • According to IDF Diabetic Atlas 2015, South Africa has about 2.3 million people with Diabetes
  • TB prevalence amongst DM patients is high (10%)
  • The incidence of multidrug resistance TB has been reported to be on the rise among DM patients